Month: November 2025

The Two Worlds of Lab Glass: Why Your Organic Chemistry Lab Doesn’t Just Use Beakers

Hand-blown Laboy Glass borosilicate lab glassware with standard taper joints in an organic chemistry distillation setup
Hand-blown borosilicate glassware with standard taper joints in a typical organic chemistry distillation setup.

When students walk into their first organic chemistry lab, most of them see
“just glass everywhere”. To me, there are really two worlds of glass in that room.

  • the familiar beakers and cylinders that look like general chemistry
  • the long condensers, three-neck flasks, and odd adapters with ground-glass joints that click together like Lego
  • most of that second group is not made in molds like beakers – it’s hand-blown from glass tubing, one piece at a time

If you only remember three things from this article, let it be these:

  1. Molded glass (like beakers) is great for gentle, everyday use at atmospheric pressure.
  2. Hand-blown glassware is built for what organic labs actually do: heat, cold, vacuum, and long, connected setups.
  3. Using “random glass” for high-temperature or vacuum work is how you end up with sudden breakage, solvent showers, and very bad days.

Two ways to make lab glass

1. Molded / pressed glass

Molded (or pressed) glassware is made by pouring or pressing hot glass into a mold. You already know this family:
beakers, graduated cylinders, Erlenmeyer flasks, petri dishes, and general-purpose storage bottles.

For atmospheric-pressure work – weighing solutions, mixing, rough volume measurements – molded glass is perfect:

  • cheap and easy to replace
  • good enough accuracy for routine volumes
  • strong enough for gentle heating on a hotplate or in a water bath

2. Hand-blown glass from tubing

Glassblower at Laboy Glass shaping hand-blown borosilicate lab glassware from tubing with a gas flame
Hand-blown borosilicate lab glassware being formed from tubing over a flame in a glass workshop.

Hand-blown glassware starts from glass tubing and rod. A glassblower uses a flame to:

  • heat sections of tubing
  • stretch, bend, and flare them
  • blow bulbs and flasks
  • fuse different pieces together
  • add standard taper joints at specific places

What hand-blown glass from tubing is good at

  • Complex shapes, no problem. Long condensers, distillation heads, multi-neck flasks and odd angles are much easier to build from tubing than to pour into a mold.
  • Wall thickness where it matters. The glassblower can keep the walls more even overall and deliberately leave a bit more thickness in the places that see the most heat or stress.
  • Proper annealing. After shaping, pieces are usually annealed so internal stresses relax instead of hiding in the glass.
  • Built-in standard joints. It’s straightforward to pull in 14/20, 19/22 or 24/40 joints and side-arms, so the pieces click together into a system.

You do pay for more labour per piece, so the unit price is higher than a simple molded beaker. In return, you get glassware that is
much more flexible for real teaching and research setups and behaves predictably when you start heating, cooling and pulling vacuum.

Complex shapes and controlled flow paths

Hand-blown borosilicate Allihn condenser from Laboy Glass with a 24/40 standard taper joint showing complex internal bulbs and flow paths
An Allihn condenser with a 24/40 standard taper joint, showing the complex internal bulbs and flow paths that are best made in hand-blown borosilicate glassware rather than molded glass.

Think about:

  • a Liebig or Allihn condenser
  • a Vigreux column
  • a Claisen adapter
  • a Dean–Stark trap

These are not “just containers”. They are carefully shaped pathways where:

  • vapours change direction and condense
  • liquid levels collect to a certain height
  • flow is controlled through narrow sections

Those shapes simply aren’t practical to make by pouring glass into a mold. They’re born from tubing and flame.

What it looks like when glass fails

Damaged round-bottom flask with a network of internal cracks while sitting in a dark solvent bath on a hotplate
Example of a damaged round-bottom flask: a network of internal cracks appearing after repeated heating and solvent exposure in a bath. This is the kind of failure you want to avoid by choosing the right glassware for the job.

From the outside, molded and hand-blown pieces may both look like “just glass”. Inside, they behave very differently once you
start pushing them: longer heating, higher temperatures, vacuum and repeated cycles.

When glass has hidden stress, is too thin in the wrong places, or was never meant for that kind of job, you see things like:

  • fine “crazed” crack patterns appearing during or after heating
  • sudden star cracks at the bottom of a flask
  • implosion under vacuum, especially near joints and sharp transitions

Good hand-blown borosilicate, properly annealed and matched to the task, is not magic – it still needs to be inspected and retired when damaged –
but it gives you a lot more safety margin than random glass of unknown origin.

Different types of hand-blown glassware brands

Once you start shopping for hand-blown glassware, you’ll meet a lot of brand names. Instead of memorising logos, it can help to think in terms of
brand types and what you gain or lose with each.

Brand type Typical examples What you usually get For university organic teaching labs
Long-established catalog brands Chemglass, Wilmad-LabGlass Very consistent dimensions, broad support for teaching & research, strong warranty and technical documentation Recommended as a backbone for demanding high-vacuum / high-temperature work if budget allows
Value-oriented hand-blown brands Laboy Glass and similar suppliers True hand-blown borosilicate with standard taper joints, complete 19/22 or 24/40 sets at a lower price point; product quality suitable for research use and already adopted by hundreds of universities and research institutes. Recommended as a budget-friendly option for equipping multiple teaching hoods with full organic glassware kits
Marketplace-driven “big seller” brands StonyLab and other Amazon-focused labels Very wide catalog, aggressive pricing, fast fulfillment through large platforms Not recommended as the primary supplier for university organic teaching labs; more suitable for low-risk, non-critical uses

This is not a formal ranking; each type has a place. In practice, many teaching labs mix them: a few high-end pieces where tolerances really matter,
and solid, value-oriented hand-blown glass for the everyday workhorses.

Bringing it back to your own lab

If you are setting up or upgrading an organic teaching lab, the key questions are simple:

  • Where do we really need the performance of hand-blown borosilicate?
  • Where are molded beakers and cylinders perfectly fine?
  • How will we inspect and retire damaged glassware before it fails in a student’s hands?

Answer those honestly, choose glass that matches the job, and a lot of “mystery breakage” and bad days in the hood simply disappear.

The Two Worlds of Lab Glass: Why Your Organic Chemistry Lab Doesn’t Just Use Beakers

A student-friendly guide to the “two worlds” of lab glass in organic chemistry. Learn the difference between molded and hand-blown borosilicate glassware, why it matters for heat and vacuum, and how to choose brands that balance safety, performance, and budget.

Most students walk into their first organic chemistry lab and see just glass everywhere.

Look closer, though, and there are actually two worlds of glass sharing the same bench space, each with a completely different purpose and personality.

TL;DR

  • Beakers & cylinders → molded glass, cheap, great for everyday mixing at atmospheric pressure.
  • Condensers, jointed flasks, adapters → hand-blown borosilicate, engineered for heat, cold, vacuum, and complex setups.
  • Using molded glass under heat or vacuum is unsafe. Organic labs rely on hand-blown glass because it’s built for those stresses.

From “Just Glass” to Two Different Worlds

I’ll never forget the first time I walked into an organic chemistry lab. Most students just see “glass everywhere.” But after years of working with it, I see something very different: two distinct worlds sharing the same bench space.

On one side, you have the familiar faces from general chemistry—beakers and graduated cylinders. They’re the reliable, everyday soldiers.

On the other side lies the real magic: long condensers, three-neck round-bottom flasks, distillation heads, vacuum adapters—pieces with standardized joints that click together like scientific Lego.

Here’s the secret most students don’t learn until later:

Those complex pieces aren’t stamped out of molds. They’re hand-blown—born from flame, skill, and careful annealing.

If you remember only three points from this article:

  1. Molded glass is perfect for gentle, everyday work.
  2. Hand-blown borosilicate is designed for heat, cold, vacuum, and modular systems.
  3. Using the wrong glass under stress can cause sudden breakage, solvent sprays, or dangerous implosions.

The Two Personalities of Lab Glass

Think of lab glassware not as different “types,” but as different crafts.

Molded Glass: The Mass-Produced Workhorse

Molded glass is made by pouring molten glass into a metal mold—like baking a cake in a pan.

Common pieces

  • Beakers
  • Graduated cylinders
  • Erlenmeyer flasks
  • Petri dishes
  • Simple storage bottles

Strengths

  • Very inexpensive
  • Durable for everyday mixing, measuring, and storage
  • Easy for teaching labs to stock in large numbers

Weaknesses

  • Walls may be slightly uneven
  • Strength depends on perfect annealing—shortcuts leave hidden stress
  • Cannot form precise standard taper joints
  • Poor performance under vacuum or extreme temperature change

Most importantly, mold cooling creates internal stresses you can’t see—but the glass will certainly “feel” them under heat or vacuum.

Molded glass is perfect for a calm day at atmospheric pressure. Push it beyond that, and it may just let you down.

Hand-Blown Glass: The Artisanal Athlete

Close-up of an Allihn condenser with standard taper joint and clip in an organic chemistry lab
Hand-blown condensers and adapters use standard taper joints so pieces from different sets can click together like a modular system.

This is where the craft begins.

A glassblower starts with a simple borosilicate tube, heating it in a flame to stretch, bend, flare, and shape it. They fuse pieces together and finish with standardized joints (14/20, 19/22, 24/40).

Why it matters

  • Complex shapes are easy. Allihn condensers, multi-neck flasks, cold traps, custom adapters—shapes impossible to mass-produce in molds.
  • Engineered strength. The blower controls wall thickness and reinforces stress points.
  • Proper annealing. The piece is heated and cooled in a kiln to remove internal stress—critical for vacuum safety.
  • Part of a modular system. Every joint is designed to be compatible with global standards.

Yes, hand-blown glass costs more. But you’re paying for precision, safety, and reliability under extreme conditions.

What Organic Labs Actually Do to Glass

Students see “a container.” Experienced chemists see a component in a high-stress system.

1. Thermal Shock

Going from an ice bath to a 200 °C oil bath can shatter poorly annealed or uneven glass. Hand-blown borosilicate expands evenly and can survive these transitions far better.

2. The Crush of Vacuum

Vacuum doesn’t “pull” glass apart—it crushes it inward. Any weak spot—a bubble, thin area, or sharp transition—can fail suddenly.

Damaged round-bottom flask collapsed in an oil bath after vacuum and thermal stress
An example of glassware that failed under combined thermal and vacuum stress—this is why annealing quality and wall thickness control matter.

My golden rule: If I don’t know its history, it never touches my vacuum line. Unknown glass is a silent liability.

3. The Lego Principle

Organic chemistry rarely uses a single piece of glass. You build reflux systems, distillation trains, Schlenk-line assemblies, vacuum filtrations, and multi-step setups.

This only works when every jointed piece from different brands fits and seals consistently. That’s the promise of hand-blown systems.

A Quick Safety Checklist

Before starting your experiment, ask:

  • Heat or extreme cold? → Use hand-blown borosilicate.
  • Vacuum or pressure? → Hand-blown only. Never risk “mystery glass.”
  • Visible damage? Star cracks, chips, large bubbles, deep scratches? → Retire immediately.
  • Room-temperature mixing/storage? → Molded beakers or bottles are perfect.

When in doubt, ask yourself: Would I stand in front of it during vacuum or heating? If not, it doesn’t belong in your hood.

Choosing Your Glass Allies: A Practical Brand Guide

Glassblower shaping borosilicate tubing in a flame to make hand-blown laboratory glassware
Hand-blown borosilicate glassware being shaped in flame before annealing. Every joint and contour is crafted with purpose.

Once you move beyond simple beakers and start building complex setups, the brand of glassware you choose becomes a critical decision. It’s not just about budget; it’s about trust. From the assemblies I’ve used and seen in labs around the world, the landscape of hand-blown glass breaks down into three clear tiers.

The Gold Standard: When Failure Is Not an Option

Brands like Chemglass and Wilmad-LabGlass set the benchmark.

Why people choose them

  • Extremely tight dimensional consistency
  • Excellent joints and finishing
  • Strong support for custom apparatus

If your lab runs demanding, high-vacuum or high-temperature experiments every day, this level of craftsmanship earns its price.

The Smart Value Tier: Reliable Performance Without the Premium

Not every teaching lab or startup research group has a research-institute budget. This is where Laboy Glass and similar value-oriented makers fill an important niche.

What they get right

  • True hand-blown borosilicate 3.3
  • Proper standard taper joints
  • Consistent performance for most academic and routine synthetic work
  • Allows departments to equip every bench affordably

This tier offers dependable, safe, and compatible glassware without premium pricing—and that’s why you’ll now find it widely used across universities and teaching labs.

Marketplace Bargains: When Low Price Carries Hidden Risk

The internet is full of ultra-cheap glassware from marketplace-driven brands. Some pieces are usable, but quality and annealing consistency can vary significantly.

For procurement: treat unusually low prices with healthy caution. In organic chemistry, glassware is safety equipment. If you don’t know the annealing history or joint precision, you don’t know whether the glass will behave safely under stress.

The Bottom Line

Organic chemistry doesn’t use hand-blown glass because it looks elegant. It uses it because it’s engineered for the realities of synthetic work—heat, cold, vacuum, modularity, and safety.

Glassware isn’t just something that holds chemicals. It’s a partner you rely on when the experiment gets real.

How to choose gloves to protect your skin from chemicals

Not all lab gloves give the same protection. This guide shows how to choose gloves to protect your skin from chemicals: understand incidental vs extended contact, match glove material and thickness to your reagents, and avoid common mistakes like wearing contaminated gloves for too long.


When you work with organic reagents, you need to choose gloves to protect your skin from chemicals, not just “whatever box is on the bench”. Start by thinking about what you’re handling, whether the contact is incidental or extended, and how long you need protection. Then match glove material, thickness and cuff length to the job, and change gloves as soon as they are contaminated or damaged.

0. Quick buying guide: glove types & example use (for busy readers)

This section is for readers who mainly want to choose gloves to protect your skin from chemicals quickly. The detailed explanation comes after the table.

You can turn the table below into an affiliate block by replacing “Example product” with real products and adding your affiliate links.

In this situation… Choose this type of glove Example product (affiliate)
Weighing solids, making small transfers, or briefly handling common organic solvents (such as acetone, ethanol, ethyl acetate, hexane). Type of contact: incidental.
Use: thin disposable nitrile exam gloves.
Look for: powder-free, about 3–5 mil thickness, good fit, basic chemical-resistance data for common solvents. Not for immersing your hands in liquids. 		Medical Soft Max™ Nitrile Exam Gloves, 100 count, blue, latex-free and powder-free
Washing glassware with solvent, or frequently handling bottles and flasks that may have solvent on the outside. Type of contact: incidental → borderline extended.
Use: thicker disposable nitrile gloves.
Look for: 6–8 mil or above, preferably with an extended cuff; better tear resistance and longer breakthrough time than thin exam gloves. 		TitanFlex Heavy Duty Black Nitrile Disposable Gloves, 8 mil, raised diamond texture
Longer tasks with one or two specific solvents (for example ketones or esters), where splashes are likely. Type of contact: extended.
Use: reusable chemical-resistant gloves — often butyl rubber for ketones/esters, or nitrile / neoprene depending on the solvent.
Look for: listed in the manufacturer’s chemical-resistance chart for your solvent, and rated for extended contact. Often worn over thin nitrile inner gloves. 		Guardian CP-14 Smooth Finish Butyl Gloves, long cuff, large size
Working with strong acids or bases, especially when heated or in larger quantities. Type of contact: extended.
Use: neoprene or heavy-duty nitrile chemical-resistant gloves.
Look for: clearly labelled for strong acids/bases, with cuffs long enough to overlap the lab coat sleeve. 		Heavy-duty neoprene–rubber chemical-resistant gloves (2 pairs), long cuff, EN 374 rated
Handling very hazardous chemicals that are readily absorbed through the skin (certain carcinogens or highly toxic reagents). Type of contact: extended, high hazard.
Use: multilayer laminate gloves (for example Norfoil / Silver Shield) over thin nitrile gloves.
Look for: broad-spectrum laminate glove used as an outer layer, plus disposable nitrile inside for comfort and easier removal. Always follow your local safety officer’s advice. 		Optional: Honeywell North Silver Shield multilayer laminate gloves (PE/EVOH), long cuff

On ChemNorth, we only link to gloves that have at least basic chemical-resistance information available. The examples are not the only correct options; always check the SDS and your lab’s PPE rules.

1. Why glove choice matters in a chemical lab

In an organic chemistry lab, gloves are one of the simplest ways to protect your skin from chemicals, but only if they are chosen and used properly.

The wrong gloves can:

  • Give a false sense of security if they permeate quickly.
  • Fail silently – a thin glove can let solvent through long before it tears.
  • Spread contamination if you keep using them after a spill.

This guide shows how to choose gloves to protect your skin from chemicals in everyday lab work, especially organic chemistry, so that your PPE matches the real risks of your experiments.

2. Step 1 – Understand your exposure: incidental vs extended contact

Most university glove guides start by distinguishing two basic situations:

  • Incidental contact
    • Small splashes, short handling of bottles, brief contact when weighing or transferring.
    • Typical of many student labs and quick bench tasks.
  • Extended contact
    • Hands immersed in liquids or cleaning baths.
    • Handling heavily contaminated items.
    • Long tasks with the same hazardous liquid where permeation time matters.

Thin disposable gloves are designed primarily for incidental contact, not for keeping your hands in solvent for an hour.

Before you choose gloves, ask:

  1. What chemicals am I using?
    • Look at each SDS (Safety Data Sheet).
    • Note whether the chemical is corrosive, irritating, toxic, or absorbed through skin.
  2. How will I be using them?
    • Small volumes vs. large quantities.
    • Occasional splashes vs. continuous handling.
  3. Do I expect incidental contact, or extended contact?
    • If extended contact is likely, you will need more substantial gloves than thin disposables.

3. Step 2 – Choose glove material

No single glove material protects against all chemicals. Always check:

  • The SDS recommendations for glove type.
  • The manufacturer’s chemical-resistance chart for breakthrough times.

Below are the most common materials in organic labs.

3.1 Nitrile – everyday workhorse for organic labs

For most organic chemistry teaching and research labs, nitrile is the standard disposable glove material:

  • Good resistance to many organic solvents, oils and greases.
  • Better puncture resistance than latex.
  • Latex-free – suitable for people with natural rubber allergy.
  • Widely available in different thicknesses and cuff lengths.

Limitations:

  • Strong oxidising acids and some aggressive solvents can still permeate nitrile.
  • For long or heavy exposure, you may need thicker nitrile or a different material.

Thin nitrile exam gloves are suitable for incidental contact with many common lab chemicals – not for immersing your hands in solvent.

3.2 Latex – dexterity but limited chemical protection

Natural rubber latex gloves:

  • Have excellent flexibility and dexterity.
  • Are widely used for biological and water-based work.

However:

  • Many organic solvents permeate latex quickly.
  • Latex can cause allergic reactions in some users.
  • For organic lab work, latex offers limited chemical protection and often performs poorly against organic solvents.

In many labs, latex is avoided or restricted. For chemical protection, nitrile is usually preferred.

3.3 Neoprene, butyl, Viton® – reusable chemical-resistant gloves

For extended contact with hazardous liquids, labs often use thicker reusable gloves made from:

  • Neoprene – good for some acids and solvents.
  • Butyl rubber – useful for ketones and esters.
  • Viton® – good for certain aggressive organic solvents and chemicals.

These gloves are usually worn over a thin nitrile glove:

  • The inner nitrile glove improves comfort and makes removal easier.
  • The outer glove provides the main chemical resistance.

Always match the glove material to the specific chemicals you use, based on manufacturer data.

3.4 Laminate gloves (Norfoil / Silver Shield) for highly toxic chemicals

For highly toxic chemicals that are readily absorbed through the skin, many safety guides recommend multilayer laminate gloves such as Norfoil / Silver Shield as an outer layer:

  • Broad-spectrum resistance to a wide range of chemicals.
  • Stiff, with poor fit and limited dexterity.
  • Often worn over a thin nitrile glove to maintain some finger movement.

These gloves are usually used for special high-hazard cases, not for everyday bench work.

4. Step 3 – Thickness, cuff length and fit

Even within the same material (e.g. nitrile), design details matter.

4.1 Thickness

  • Thin exam nitrile (≈ 3–5 mil / 0.07–0.12 mm)
    • Good dexterity.
    • Suitable for weighing, short transfers and general incidental contact.
    • Shorter breakthrough times.
  • Thicker disposable nitrile (≥ 6–8 mil / 0.15–0.20 mm)
    • Better for longer tasks with solvents or frequent contact.
    • More robust but slightly less flexible.

For extended contact, you may need to move beyond disposables to reusable chemical-resistant gloves.

4.2 Cuff length

  • Standard cuffs protect hands and wrists in many bench-top tasks.
  • Extended cuffs help when:
    • You work inside a fume hood with raised arms.
    • You handle large volumes or corrosive liquids.
    • Your lab coat sleeves ride up when you reach forward.

4.3 Fit and size

  • Gloves that are too tight:
    • Are more likely to tear.
    • Cause hand fatigue.
  • Gloves that are too loose:
    • Reduce dexterity.
    • Can catch on glassware or equipment.

Choose the size that allows you to flex your fingers freely without feeling squeezed or swimming in extra material.

5. Step 4 – Using, changing and disposing of gloves

5.1 When to change disposable gloves

Change disposable gloves immediately when:

  • You spill or suspect contamination on the glove.
  • You move between “dirty” and “clean” tasks (e.g. from handling chemicals to using a keyboard).
  • You see tears, punctures or obvious degradation.
  • You have been working for a long time with volatile solvents, even without obvious spills.

Never wash or reuse disposable gloves.
Washing can carry chemicals through the material or damage the glove, making exposure more likely.

5.2 Reusable chemical-resistant gloves

For reusable gloves used in extended contact:

  • Inspect before and after each use for:
    • Rips, punctures, soft spots
    • Changes in colour or texture
  • If you see signs of degradation, retire the gloves immediately.
  • After use, wash the outer surface according to your lab’s procedure and let the gloves air dry in the lab, not in common areas.
  • For highly hazardous chemicals, consider wearing a thin nitrile inner glove so you can remove the outer glove first and keep a clean inner layer.

5.3 Why handwashing still matters

Even if gloves look clean when you take them off, microscopic contamination is still possible.

Always wash your hands thoroughly with soap and water after removing gloves, before you eat, drink, or leave the lab.

5.4 Disposal of used gloves

How you dispose of gloves depends on what they have touched:

  • Gloves with no contamination usually go into regular lab trash (following your local policy).
  • Gloves contaminated with hazardous chemicals should go into the designated hazardous-waste container, not standard bins.
  • Gloves contaminated with biological or radioactive materials must follow your institution’s biological or radioactive waste procedures.

When in doubt, follow your lab’s waste policy and ask your safety officer.

6. Special situations: cuts and cryogenic hazards

This article focuses on gloves that protect your skin from chemicals. Some lab tasks need additional protection:

  • Cut-resistant gloves
    • Used when handling sharp glass, metal or cutting tools.
    • Often worn under or over a chemical-resistant glove when both mechanical and chemical hazards are present.
  • Cryogenic gloves
    • Designed for extreme cold (e.g. liquid nitrogen).
    • May be worn together with thin chemical-resistant gloves when both cold and chemical exposure are possible.

Consult your lab’s safety guidance when combining different glove types.

7. Interactive checklist

Before you start your next experiment, use this checklist to see if you have chosen the right gloves to protect your skin from chemicals:

1. Understand your exposure

2. Choose appropriate gloves

3. Use, change and dispose correctly

8. Common mistakes to avoid

You can keep this as a short section near the end:

  • Assuming any glove protects against any chemical. Always verify with SDS and manufacturer charts.
  • Wearing the wrong material for organic solvents. Latex is often not suitable for many organics.
  • Using disposable gloves for extended immersion. They are designed for incidental contact.
  • Wearing contaminated gloves “just a bit longer”. Change them immediately after a spill.
  • Touching door handles, phones and keyboards with lab gloves. This spreads contamination instead of containing it.
  • Not washing hands after removing gloves. Gloves are an extra layer, not a replacement for hygiene.

9. Further reading & affiliate disclosure

Further reading

  • Many universities publish free glove-selection charts and safety summaries. Look for chemical-resistance tables provided by glove manufacturers or your institution’s environment, health and safety office.
  • Some EHS websites also provide simple decision trees to help distinguish incidental contact vs. extended contact and choose an appropriate glove material.

Affiliate disclosure

ChemNorth sometimes uses affiliate links to products that meet the safety criteria described in this article. If you buy through these links, we may earn a small commission at no extra cost to you. We only link to gloves that provide clear specifications and basic chemical-resistance information, but you must still follow your own lab’s PPE rules.

10. Safety note

Information on ChemNorth is for educational purposes and small-lab guidance. Always follow the PPE rules, safety procedures and waste-disposal policies of your own institution or lab. When selecting gloves, consult safety data sheets and glove manufacturers’ information, and ask your instructor, supervisor or safety officer if you are unsure.

How to Protect Your Skin from Chemicals in the Organic Lab


In an organic lab, you need to protect your skin from chemicals, not just your eyes and lungs. Many organic reagents can irritate or be absorbed through the skin, so hand protection is more than just a formality. To reduce risk, wear suitable gloves whenever you handle liquids or solids that could harm the skin, avoid touching door handles, phones or pens with contaminated gloves, and wash your hands thoroughly after removing them.

Skin contact with chemicals is one of the most common types of exposure in the organic lab. Sometimes the effects are immediate, like irritation or burns. In other cases, absorption through the skin may be slow and less obvious. This article focuses on practical habits and glove use that help you protect your skin in routine lab work.

1. How chemicals reach your skin

Common pathways include:

  • Direct splashes or spills during pouring, transferring or cleaning;
  • Handling contaminated glassware, benches or equipment;
  • Touching your face or hair with contaminated hands or gloves.

You cannot always control what a previous user has left behind, but you can control how you handle materials and how quickly you respond when something goes wrong.

2. When you should wear gloves

You should wear suitable protective gloves when:

  • Handling liquid organic reagents or solvents;
  • Working with corrosive or irritant chemicals;
  • Cleaning up spills or wiping contaminated surfaces;
  • Handling waste containers that may have residues on the outside.

You may not need gloves for every dry, solid material or for tasks like writing in your notebook, but when in doubt, ask your instructor.

3. Everyday habits to protect your skin from chemicals

To protect your skin from chemicals in everyday lab work, start with three habits…

3.1 Putting on and taking off gloves

  • Check gloves for holes or tears before use.
  • Pull them over the wrist so there is minimal gap between glove and lab coat sleeve.
  • When removing, peel them off from the wrist inside-out, avoiding contact with the outside surface.

3.2 Keeping gloves from spreading contamination

Gloves protect your skin, but they can spread contamination if you are not careful.

Avoid:

  • Touching door handles, phones, keyboards or notebooks with contaminated gloves;
  • Handling clean glassware or personal items while still wearing gloves;
  • Leaving gloves on when you have stopped working with chemicals.

Adopt a simple rule:

Anything you would happily touch with your bare hands should not be touched with contaminated gloves.

4. Responding to skin contact

If a chemical reaches your skin:

  1. Act immediately – do not wait to see whether it hurts.
  2. Rinse the affected area under running water for at least 10–15 minutes.
  3. Remove contaminated clothing or jewellery if possible.
  4. Inform your instructor or supervisor and follow the lab’s incident procedure.

For serious exposures, local emergency procedures always take precedence over any general advice.

5. Choosing gloves to protect your skin from chemicals

In many labs, nitrile gloves are the default choice because they resist a wide range of organic solvents better than natural latex. However, no single glove material is perfect for every chemical.

For now:

  • Use the glove type recommended by your lab or instructor for the chemicals you handle.
  • Do not assume that a glove is safe for all substances; permeation times vary widely.
  • Replace gloves promptly if they become torn, heavily contaminated, or if you have worked with aggressive solvents for a significant time.

Later on ChemNorth we will look at glove selection charts and material compatibility in more detail.

6. Checklist: skin protection in everyday work

Use this short checklist whenever you want to check whether you really protect your skin from chemicals during a lab session.

Before

  • I know which tasks require gloves today.
  • I have appropriate gloves available and they are intact.
  • My lab coat sleeves cover my arms.

During

  • I wear gloves when handling liquids and hazardous solids.
  • I avoid touching personal items and clean surfaces with contaminated gloves.
  • I change gloves if they become torn or heavily contaminated.

After

  • I remove gloves correctly and dispose of them in the proper container.
  • I wash my hands thoroughly with soap and water.
  • I report any skin contact that required rinsing.

7. Safety note

Information on ChemNorth is for educational purposes and small-lab guidance. Always follow your institution’s safety rules and local regulations, and ask your instructor or safety officer if you are unsure about a procedure.

How a Fume Hood Protects You in the Organic Chemistry Lab (and How to Use It Properly)

Summary
In an organic chemistry lab, a fume hood is a local exhaust device designed specifically to handle organic vapours, corrosive gases and hazardous dusts. You work outside the hood while your apparatus sits inside; the hood draws contaminated air away and discharges it safely. Using it correctly means knowing when to work inside the hood, how to set it up, and how to avoid turning it into a storage shelf.

1. What is a fume hood in an organic chemistry lab?

In an organic lab, a fume hood is a ventilated enclosure that provides local exhaust for hazardous air contaminants. It is designed so that:

  • You stand outside the hood.
  • Your glassware and apparatus are set up inside the hood.
  • Air flows from the room, past the front opening, through the hood, and out via a duct and fan system.

Typical features of a chemical fume hood:

  • A movable front sash (glass window) that you can raise or lower.
  • A work surface and interior lining made of materials resistant to chemicals and solvents.
  • Services inside the hood:
    • Water, gas and vacuum outlets
    • Electrical sockets
  • In many modern hoods:
    • Explosion-resistant lighting
    • Airflow indicators or alarms
    • Sometimes a digital face velocity display

Functionally, the purpose is simple:

Let hazardous vapours and gases “live inside the hood” and be exhausted, instead of entering your breathing zone or the rest of the lab.

2. What problems does a fume hood solve in organic work?

In organic chemistry, a fume hood primarily addresses four safety issues.

2.1 Preventing inhalation of organic solvent vapours

Many common solvents are volatile and hazardous to inhale, especially in poorly ventilated spaces:

  • Diethyl ether, THF
  • Dichloromethane, chloroform
  • Benzene, toluene, hexane, petroleum ether
  • Acetone and other ketones

Typical operations that should be done in a fume hood:

  • Distillation and reflux with volatile solvents
  • Concentrating solutions, rotary evaporation of larger volumes
  • Liquid–liquid extractions with volatile, toxic or smelly solvents
  • Pouring or transferring significant volumes of solvent

2.2 Reducing exposure to toxic or irritating gases

Certain reagents and reactions generate corrosive or toxic vapours, such as:

  • Acid fumes from hot HCl, HBr, HNO₃, H₂SO₄
  • Thionyl chloride (SOCl₂), POCl₃, oxalyl chloride, acid chlorides
  • Bromine, ammonia and other pungent gases

These can severely irritate the eyes and respiratory tract and may have systemic toxicity. A fume hood keeps most of these vapours within the enclosure and removes them through the exhaust system.

2.3 Lowering fire and explosion risk

Organic labs use many flammable solvents (ether, hexane, petroleum ether, etc.). In a confined, unventilated area, vapours can reach flammable or explosive concentrations and be ignited by:

  • Open flames
  • Hot surfaces
  • Electrical sparks

A properly working fume hood:

  • Dilutes and removes solvent vapours quickly
  • Helps keep vapour concentrations below flammable limits
  • Provides a partial physical barrier (sash glass) that can help deflect minor splashes or small incidents
    (Although it is not a true blast shield.)

2.4 Preventing contamination of the lab environment

Without a hood, volatile and odorous substances can quickly spread through the entire room:

  • Volatile amines
  • Sulfur compounds
  • Acid anhydrides and other strongly smelling reagents

A fume hood keeps most of these confined to the interior and ductwork, reducing persistent smells and contamination on walls, instruments and other people’s experiments.

3. Common fume hood types in organic labs

Fume hoods can be categorised in several ways. For typical organic chemistry teaching and research labs, a few combinations are most relevant.

3.1 Ducted vs ductless

Ducted fume hood (the standard choice)

  • Air from the hood is drawn through ducting by a fan and exhausted to the outside.
  • Handles mixtures of organic vapours, acid/base fumes and other gases (provided duct materials are suitable).
  • Requires building ventilation design and installation; location is relatively fixed.

This is the mainstay of organic chemistry labs.

Ductless (recirculating) fume hood

  • Air passes through filters (often activated carbon) and is then returned to the room.
  • Filter performance depends strongly on the specific chemicals and load.
  • Not suitable as the primary hood for mixed organic synthesis with varied solvents and high vapour loads.
  • Requires strict control and monitoring of filter saturation.

For most organic labs, a ducted chemical fume hood is considered the appropriate standard.

3.2 Constant air volume (CAV) vs variable air volume (VAV)

CAV (Constant Air Volume) fume hood

  • The fan delivers approximately constant total airflow.
  • When you raise the sash (larger opening), the face velocity tends to drop.
  • When you lower the sash, the face velocity rises.

Pros:

  • Simpler design, lower initial cost.

Cons:

  • Face velocity varies with sash position.
  • Energy use is higher, especially with many hoods.

VAV (Variable Air Volume) fume hood

  • A control system adjusts airflow to keep face velocity roughly constant, regardless of sash height (e.g. around 0.5 m/s).

Pros:

  • More stable containment over different sash positions.
  • Better for building energy efficiency.

Cons:

  • More complex and expensive; requires proper maintenance.

In many teaching labs and smaller facilities, CAV hoods are common. In large research buildings or new lab complexes, VAV systems are often used.

3.3 Bench-top vs walk-in

Bench-top fume hood

  • The most common type in organic labs.
  • Mounted on a bench or dedicated base cabinet.
  • Suited for typical glassware setups:
    • Reflux
    • Distillation
    • Vacuum filtration
    • Small reactors

Walk-in fume hood

  • The floor of the hood is close to the room floor.
  • Allows you to roll in large equipment, drums or pilot-scale setups.
  • Usually used for scale-up or specialised operations, not routine small-flask work.

4. When must you work in a fume hood?

As a practical guide, perform work in a fume hood if any of the following apply:

  • You are using or generating significant amounts of volatile organic solvents.
  • You work with toxic, corrosive, strongly irritating or odorous gases or vapours.
  • The reaction may be strongly exothermic or prone to splashing.
  • You handle toxic powders or suspect solids that could become airborne.
  • Your lab manual or supervisor explicitly instructs you to work in the hood.

If you would not want to breathe the vapours for an hour, the hood is probably the right place.

5. Setting up the fume hood before you start

Before bringing chemicals or setting up glassware in the hood, check the following.

5.1 Confirm airflow

  • Make sure the fume hood fan is on.
  • Check any airflow indicator, gauge or alarm (if installed).
  • A simple functional check: hold a small strip of light paper at the front opening and confirm it is drawn steadily into the hood.

If you suspect poor airflow, do not start hazardous work. Inform your instructor or lab supervisor.

5.2 Set the sash to the recommended height

  • Most hoods have a marked safe working height (often around 25–30 cm opening).
  • Work with the sash at or below this mark.
  • Do not automatically raise the sash to full height “for convenience”: this reduces containment.

5.3 Clear clutter and lay out your setup

  • Remove bottles, boxes and equipment that are not needed for the current experiment.
  • Place your apparatus:
    • At least 10–15 cm inside the front edge
    • Away from the direct line of the baffles or slots at the back, without blocking them completely
  • Clamp glassware securely; make sure heating mantles and stirrer plates sit flat and stable.

Remember: the fume hood is not a solvent warehouse. Long-term storage of many bottles inside reduces performance and increases risk.

6. Good practice while working in the hood

6.1 Where you stand and how you move

  • Keep your head and upper body outside the hood.
  • Look through the sash glass and reach through the opening with your arms.
  • Move your hands and arms smoothly; avoid rapid in-and-out motions that can disturb airflow at the face.

Frequent fast movements, opening doors or placing the hood right next to a busy doorway can create turbulence that pulls fumes out towards the room.

6.2 Heating and flames

  • Prefer electric heating: hot plates, heating mantles, oil baths, sand baths.
  • Avoid open flames (Bunsen burners, alcohol lamps) when flammable solvents are present.
  • If a flame must be used (in rare, controlled situations), ensure:
    • Flammable solvent bottles are capped and kept well away.
    • No significant solvent vapours are being generated at the same time.

Never leave heated flammable solvent systems running unattended in the hood.

6.3 Avoiding “storage mode”

  • Do not use the hood as a permanent home for solvent bottles, waste containers or surplus glassware.
  • Long-term storage reduces the free working area and can compromise airflow patterns.
  • Keep only what you need for the ongoing experiment inside; remove the rest.

7. After you finish: shutting down properly

When your experiment is complete:

  1. Allow time for purge
    • Keep the fan running for some minutes (often 5–15 minutes, depending on lab policy) after you stop generating vapours.
    • This helps clear residual contaminants.
  2. Remove or close chemicals and waste
    • Cap reagent bottles and waste containers.
    • Remove them from the hood to their designated storage or waste area if appropriate.
  3. Clean the work surface
    • Wipe up spills with suitable materials and cleaners, following your lab’s procedures.
    • Dispose of contaminated cleanup materials as chemical waste if required.
  4. Lower the sash
    • When not in use, the sash should be closed or lowered as far as your lab policy allows.
    • This improves safety and reduces energy consumption.

8. Quick checklist: using the fume hood wisely

You can adapt this into a clickable checklist later if you like. For now, it works as a simple self-check.

Before you use the fume hood for an experiment, run through this quick checklist:

Before starting

While working

After finishing

9. Safety note

Information on ChemNorth is intended for educational purposes and small-lab guidance. Always follow your institution’s safety rules, equipment manuals and local regulations. If you are unsure whether a procedure should be carried out in a fume hood, ask your instructor, lab supervisor or safety officer before proceeding.

How to Check and Retire Damaged Glassware Safely

Summary
Before you start any experiment, take a moment to inspect your glassware. Any visible crack or chip – anywhere on the piece – is a reason to stop using it. This is especially important for vacuum and thick-walled vessels. Retire damaged items, place broken glass in the correct waste container, and choose appropriate glassware for demanding hot–cold or vacuum work to reduce the risk of cuts and implosions.

1. Why damaged glassware matters

Damaged glassware is more than an aesthetic problem. It adds two kinds of risk to the lab:

  • Cuts and punctures – sharp chips on rims, joints or broken edges can easily cut hands or fingers.
  • Sudden failure during use – cracks can propagate when glass is heated, cooled, clamped or put under vacuum, sometimes leading to breakage or implosion.

The cost of a replacement flask or beaker is always lower than the cost of an injury, lost sample, or damaged equipment. A simple inspection habit before each experiment prevents many avoidable accidents.

2. A simple inspection routine before you use glassware

Do a quick but systematic check before you set up:

2.1 Look along all critical edges

Check every edge that you might touch or that must seal:

  • Rims of beakers, flasks and test tubes
  • Ground-glass joints (inner and outer)
  • Stopcocks and valves
  • Hose barbs, sidearms and adapters

Look for:

  • Chips, missing “bites” of glass
  • Rough or sharp spots
  • White, frosted areas that were not originally ground

2.2 Scan the whole body, not just the rim

Any part of the glass can crack, not only the edge. Inspect:

  • The body of flasks and bottles for straight cracks, curved cracks or “spider-web” patterns
  • The neck and shoulders where the shape changes
  • Side arms and joint transitions, where the wall thickness changes
  • The base for star cracks – radiating lines that start from a point of impact

Rotate the item slowly in good light, or against a dark background, to catch reflections from fine cracks.

2.3 Use your fingers carefully

With clean, dry fingers:

  • Run a fingertip very lightly around rims and joints to feel for nicks
  • Avoid pressing hard or sliding quickly – you are checking, not polishing
  • If a spot feels sharp or irregular, examine it closely in the light

Rule of thumb:

If you can clearly see or feel a crack or chip anywhere on the glass, do not use that item for experiments.

Before you use any piece of glassware, run through this quick checklist:

Check all edges

Check the body and base

Extra care for vacuum and thick-walled glass

3. When a piece must be retired

In a teaching or research lab, it is safer to retire glassware early rather than “see how long it lasts”. Retire an item immediately if you notice:

  • Any visible crack, however short, on the body, neck, joint, side arm or base
  • A chip or missing piece on any rim, ground joint or stopper
  • A star-shaped crack on the bottom or side
  • A joint that no longer seals properly because the glass is visibly worn or chipped
  • Any item that has experienced a strong impact and is now suspected to have hidden damage

For most labs, the safest policy is:

If in doubt, throw it out.

Label suspect glassware clearly (for example, with tape marked “BROKEN / DISCARD”), remove it from the cupboard so it cannot be used by mistake, and move it towards the correct waste route.

4. Special case: vacuum and thick-walled glassware

Vacuum operations and pressure differences place extra stress on glassware.

  • Under reduced pressure, the outside air pushes inwards. Cracks act as stress concentrators, making implosion more likely.
  • Thick-walled glassware such as vacuum flasks, Schlenk lines, cold traps and filter flasks is designed to handle this stress only when it is free of defects.

For vacuum-rated glassware:

  • Inspect before every use – pay special attention to the body, neck and any branches.
  • Never use a piece with visible cracks, chips or star patterns, even if they look small or “stable”.
  • Use guards where available: safety shields, blast screens, or protective cages around large vacuum vessels.
  • Do not rely on tape or plastic film to “hold it together”. These do not restore the strength of the glass.

Once a vacuum vessel has any visible defect, it should be permanently retired from vacuum service. In most labs, the safest approach is to discard it completely rather than downgrade it to non-vacuum use, to avoid confusion later.

Quick question

You are about to set up a vacuum distillation using a thick-walled 100 mL round-bottom flask. When you inspect it, you notice a short, fine crack near the shoulder of the flask that is clearly visible in the light. What should you do?

  1. A. Use the flask anyway but reduce the vacuum level.
  2. B. Wrap tape or film around the crack and then use the flask.
  3. C. Retire the flask from service and choose an undamaged vacuum flask.
Show suggested answer

Retire the flask from service and choose an undamaged vacuum flask.
Any visible crack in a vacuum-rated vessel is a serious hazard, because stress is concentrated at the defect and can lead to implosion under reduced pressure. Tape or lower vacuum do not restore the original strength of the glass. The safest option is to remove the damaged flask from use and replace it with an intact, properly rated vacuum flask.

5. How to deal with damaged or broken glass

5.1 Damaged but still in one piece

If a piece is intact but damaged:

  1. Stop using it immediately.
  2. Mark it clearly (for example, with tape or a label saying “BROKEN / DISCARD”).
  3. Place it in the designated area for broken glass, or in a container waiting to be emptied into the glass waste bin.
  4. Inform the lab supervisor if local rules require it.

Do not put damaged glass back in the cupboard “to think about later”. It will eventually be picked up by someone who assumes it is fine.

5.2 Completely broken glass

When glass breaks:

  • Warn people nearby so they do not step on fragments.
  • Wear appropriate gloves and closed shoes.
  • Use tongs, forceps, a brush and pan, or a piece of stiff cardboard to collect fragments. Avoid picking up shards with bare hands.
  • Place all pieces into the designated glass-waste container – not into normal trash bags, where they can injure cleaning staff.
  • If glass is contaminated with chemicals, follow your lab’s procedure for chemical-contaminated glass waste (for example, labelled glass waste containers or special bags).

A rigid, puncture-resistant glass waste container is standard in most labs. It protects everyone who handles waste downstream.

6. Choosing glassware for demanding heating and cooling

Thermal shock resistance depends mainly on the type of glass. For most high-quality labware, this means borosilicate 3.3 glass, which tolerates heating and cooling better than ordinary soda-lime glass.

Within the same glass type, the way glassware is made also matters:

  • Blown or flame-worked glassware tends to have more uniform wall thickness and smoother transitions between sections. This helps distribute thermal stress more evenly.
  • When such pieces are properly annealed after forming, internal residual stress is reduced, so they are less likely to crack under rapid heating or cooling.

For applications that combine high temperatures with repeated hot–cold cycling – such as reflux, distillation, or heating and then quenching – it is often safer to:

  • Use well-annealed, blown borosilicate glassware explicitly specified for those conditions,
  • Avoid heavy moulded pieces with sharp changes in thickness where thermal stress can concentrate.

This does not mean moulded glassware is unsafe; it is perfectly adequate for many routine tasks. The key is to match the design and specification of the glassware to the temperature and thermal-shock conditions of your experiment, and to continue inspecting pieces regularly over their lifetime.

Why You Must Never Eat, Drink or Mouth-Pipet in the Lab

Summary
In a lab, anything that reaches your mouth can carry invisible chemical or biological contamination. Eating and drinking in the lab, or pipetting by mouth, turns that invisible risk into a direct exposure. Modern lab safety rules ban food and drink in experimental areas, forbid mouth pipetting, and require thorough handwashing before you leave the lab or touch food. Second-hand and returned glassware also demand extra care: treat them as potentially contaminated until they are properly cleaned.

1. How chemicals reach your mouth in a lab

When people think about chemical exposure, they often focus on spills or fumes. But one of the most straightforward and dangerous routes is ingestion – chemicals entering through your mouth and digestive tract.

In a lab, this can happen in several ways:

  • Tasting or “checking by mouth”
    Historically, some chemists really did taste small amounts of substances to identify them. Today, this is recognised as unnecessary and unsafe.
  • Mouth pipetting
    Drawing liquids into a pipette by sucking with your mouth can send the liquid, aerosols or vapour directly into your mouth or throat if you misjudge the volume or lose control.
  • Contaminated hands touching food, drinks or your face
    You handle glassware, reagents, second-hand or returned items, and then:
    • eat a snack,
    • drink water or coffee,
    • touch your lips or wipe your mouth
      without washing your hands thoroughly.
  • Food and drink stored or opened in the lab
    Even if you never “taste chemicals”, food and drink left on lab benches can be contaminated by splashes, vapour, dust or dirty gloves.

The common pattern is simple: any object that lives in the lab environment can carry residues you cannot see.

2. Why labs ban food and drink completely

Most lab safety manuals include a strict rule: no eating, no drinking, no food storage in laboratories. This is not about being strict or unfriendly; it is about breaking the most direct path for ingestion.

2.1 Invisible residues are everywhere

In a lab, many surfaces can carry small amounts of chemicals:

  • The benchtop where you work
  • Glassware, even if it “looks clean”
  • Pipettes, clamps, racks and instruments
  • Your notebook, pens and keyboard if you touch them with contaminated gloves

These residues can be:

  • Organic solvents
  • Corrosive or irritant reagents
  • Heavy metals or other toxic compounds
  • Biological materials in some labs

You cannot see or smell most of these in the small amounts that matter for chronic exposure.

2.2 A real-world lesson: eating after handling glassware

In one glass factory, a worker was asked to check returned glassware that a customer had sent back. He handled the glass instruments with bare hands to inspect them, without knowing exactly what they had been used for or what residues might be present.

After the inspection, he did not wash his hands. He then picked up food and ate. Shortly afterwards, he developed signs of poisoning and later died.

We do not need the exact chemical identity to understand the chain of events:

  1. Returned or second-hand glassware may have unknown residues on the surface.
  2. Handling them with bare hands transfers residue to the skin.
  3. Eating without washing hands transfers residue from skin to mouth.

This kind of tragedy is not dramatic or exotic. It is a series of small, very ordinary decisions:

  • “I’m just touching glass, not chemicals.”
  • “I’ll eat first, wash my hands later.”

The rule “no eating or drinking in the lab, always wash hands before food” exists to break this chain.

2.3 Practical rule

Because of these risks, a safe lab policy is:

  • No food, drink, chewing gum or smoking in experimental areas.
  • No storage of food or drink in lab fridges, freezers or cabinets.
  • Eat and drink only outside the lab, after washing your hands thoroughly with soap and water.

3. Why mouth pipetting is completely banned

Mouth pipetting once was common in chemistry and biology labs. Today, it is recognised as a completely unacceptable practice.

3.1 What goes wrong when you pipet by mouth

When you suck on a pipette:

  • The liquid is very close to your mouth.
  • If you misjudge the suction or the liquid “jumps”, it can enter your mouth or throat.
  • Even if you spit it out quickly, your lips and mucous membranes have already been exposed.

In some cases, droplets or aerosols may enter your airway before you even notice.

3.2 The types of risk

The liquid you are pipetting might be:

  • A toxic organic solvent
  • A corrosive acid or base
  • A solution containing heavy metals
  • A biological sample carrying infectious agents

Historically, some laboratory-acquired infections and poisonings have been linked to mouth pipetting. This is why modern safety standards and institutional rules are unanimous: mouth pipetting is forbidden in professional labs, teaching labs and serious small labs.

3.3 Safer alternatives

Modern labs have simple tools that make mouth pipetting unnecessary:

  • Rubber pipette bulbs
  • Manual pipette controllers
  • Adjustable volume micropipettes with disposable tips

These devices:

  • Keep liquids away from your mouth
  • Give you much better control over volume
  • Are inexpensive compared to the cost of an incident

A good habit is:

If you ever see mouth pipetting in a lab, treat it as an urgent safety issue, not a matter of “style” or “speed”.

4. Second-hand and returned glassware: treat as “unknown”

Second-hand lab glassware and customer returns can be valuable resources, but they also carry invisible history.

You often do not know:

  • Exactly what was in them last time
  • Whether they were used correctly or misused as temporary containers
  • Whether residues have dried on surfaces, joints or threads

4.1 Handling second-hand or returned glassware

When you unpack or inspect second-hand or returned glass:

  • Assume that it may carry unknown contamination.
  • Whenever possible, wear appropriate gloves.
  • Avoid touching your face, phone or personal items during inspection.
  • After handling, wash your hands thoroughly before eating, drinking or leaving for a break.

This applies both in a lab that buys second-hand glassware and in a glassware factory or warehouse that handles returns.

4.2 Cleaning before use in experiments

Before using second-hand or returned glassware in experiments:

  • Put it through a thorough cleaning cycle:
    • Suitable detergent wash
    • Multiple rinses with tap water and then deionised/distilled water
    • Special cleaning procedures as required by your lab
  • If the previous use is unclear and the potential risk is high, your lab may decide to discard the item rather than reuse it.

A simple principle is:

Treat any glassware of unknown history as a potential chemical container until it has been properly cleaned.

5. Building safer everyday habits

Rules only help if they translate into daily habits. The key behaviours for reducing ingestion risk are simple but powerful:

5.1 For eating and drinking

  • Keep all food and drink out of the lab.
  • Never store food or beverages in lab refrigerators or freezers.
  • Before eating, drinking or smoking:
    • Leave the lab
    • Remove gloves and other contaminated PPE
    • Wash your hands thoroughly with soap and water

5.2 For pipetting and liquid handling

  • Never pipet by mouth, even “just water” – habits transfer across tasks.
  • Use pipette bulbs, manual controllers or micropipettes.
  • Store pipetting devices and tips in a clean area, away from direct contamination.
  • Train new lab members explicitly: “We do not mouth pipet, ever.”

5.3 For second-hand and returned glassware

  • Treat unknown glassware as contaminated until cleaned.
  • Wear gloves when inspecting or sorting.
  • Wash your hands after handling, before any break or meal.
  • Do not assume that “it’s just glass” and therefore safe.

Small actions repeated every day—no food in the lab, no mouth pipetting, washing hands—create a long-term barrier against serious incidents.

6.Checklist: before you eat, drink or leave the lab

Before you eat, drink or leave the lab, run through this quick checklist:

Have I been in contact with lab surfaces or materials?

Am I about to eat or drink?

For pipetting

7. Mini quiz: what is the real problem?

Mini quiz

Which of the following behaviours is clearly unsafe because of ingestion risk?



Show suggested answer

Inspecting returned lab glassware with bare hands in the lab and then eating a snack without washing your hands.
Returned or second-hand glassware may carry unknown chemical residues on their surfaces. Handling them with bare hands and then eating without washing transfers any contamination directly to your mouth. New glassware opened in a clean office after handwashing, and properly gloved work with sealed bottles followed by glove removal, are much lower-risk behaviours when done correctly.

8. Safety note

Information on ChemNorth is for educational purposes and for small-lab guidance. Always follow your institution’s safety rules and local regulations. If you are unsure whether a behaviour is safe, ask your instructor, lab supervisor or safety officer before proceeding.

How to Break and Insert Glass Tubing Safely in the Lab

Summary
Cutting glass tubing and inserting glass into rubber or cork stoppers are common tasks in teaching labs, but they are also a frequent cause of hand injuries. To work safely, always score and wet the glass before breaking it, wrap it in a towel or tissue when snapping, lubricate the end before insertion, and hold the glass close to the stopper while rotating gently. Never push hard on un-scored glass or hold the far end of the tube while forcing it through a stopper.

Glass tubing, thermometers and adapters are used everywhere in an organic lab. Preparing them correctly is routine work, but doing it carelessly can send broken glass into the palm of your hand. This article explains safe, step-by-step methods for breaking glass and inserting it into stoppers.

1. Why these tasks cause so many injuries

Typical injury patterns include:

  • Trying to snap un-scored glass tubing by brute force;
  • Holding the far end of a thermometer or tube while pushing it through a tight stopper;
  • Handling glass with bare hands when it suddenly breaks.

The common feature is poor control over where the force goes. Safe techniques help you control the break and keep your hands behind the line of force.

2. How to break glass tubing safely

2.1 Tools and preparation

You will typically need:

  • A glass file, glass-cutting tool or triangular file;
  • A drop of water or glycerol;
  • A towel or several layers of paper tissue.

2.2 Step-by-step procedure

  1. Mark the length you need on the glass.
  2. Score a small, clean line around the tube at that point using the file. You do not need to cut deeply; one firm stroke is usually enough.
  3. Wet the score line with a drop of water to help the crack start smoothly.
  4. Hold the tube with both hands, wrapped in a towel or paper tissue, with your thumbs placed opposite the score line.
  5. Gently bend the glass away from the score until it snaps along the line.

Do not twist or crush the glass. The force should be slow and controlled.

2.3 After the break

  • Smooth any sharp edges with fine sandpaper or a fire-polishing step if your instructor allows it.
  • Dispose of unwanted off-cuts in the broken-glass container, not in normal trash.

3. How to insert glass into rubber or cork stoppers

3.1 Why this step is risky

When you push a long piece of glass through a tight stopper, the stress concentrates near the point where it enters the stopper. If the glass breaks, the broken end can be driven toward the hand that is pushing.

3.2 Safer technique

  1. Lubricate the end of the glass with a drop of water or glycerol.
  2. Hold the stopper in one hand.
  3. With the other hand, hold the glass close to the end that enters the stopper, not at the far end.
  4. Push the glass in while rotating the stopper gently, applying slow, even pressure.
  5. Stop if resistance is very high and ask for a larger bore hole or a different adapter.

Never use sudden, strong force. Never hold the glass far away and “ram” it through.

4. Inspecting and using prepared glass

After you have prepared your glass:

  • Check that the exposed ends are reasonably smooth and free of large chips.
  • Make sure the glass sits straight in the stopper or adapter; avoid forcing it into distorted angles.
  • Handle long assemblies carefully and support them with clamps where appropriate.

5. Checklist: before, during and after

Before

  • I have the right diameter of glass tubing or thermometer.
  • I have a file, lubricant, and towel or tissue ready.
  • I know exactly how long the piece needs to be.

During

  • I always score before breaking glass.
  • I wrap the glass and keep my hands behind the line of force.
  • I hold glass close to the stopper end when inserting and rotate gently.

After

  • Off-cuts go into the broken-glass container.
  • Edges are smoothed if necessary and allowed by the lab.
  • Completed assemblies are handled and clamped carefully.

6. Safety note

Information on ChemNorth is for educational purposes and small-lab guidance. Always follow your institution’s safety rules and local regulations, and ask your instructor or safety officer if you are unsure about a procedure.

How to Use Heat Safely in an Organic Chemistry Lab

Summary
Heating is essential in organic chemistry, but it is also one of the main sources of fires and burns in the lab. To use heat safely, avoid open flames around flammable solvents, prefer hot plates and heating mantles, keep solvent bottles and waste containers away from hot surfaces, and never leave an active heater unattended. Always check glassware for cracks before heating and allow hot equipment to cool before moving or cleaning it.

When you begin experimental organic chemistry, you quickly discover that many reactions and procedures require heat. Refluxing, distillation, evaporation, and drying all depend on controlled heating. At the same time, heating is closely linked to fires, burns, and broken glassware. This article gives you a practical guide to using heat with the lowest reasonable risk in a teaching or small organic lab.

1. Why open flames are rarely a good idea

In an organic lab, open flames (Bunsen burners, alcohol lamps, lighters) are almost always the least safe heating option.

1.1 Flammable vapours travel farther than you think

  • Many organic solvents (diethyl ether, pentane, hexane, acetone, etc.) have low boiling points and high vapour pressures.
  • Their vapours are often heavier than air and can flow along the bench or near the floor.
  • A flame several metres away can still ignite a vapour cloud that drifts past it.

Because of this behaviour, many organic labs adopt a simple rule:

No open flames when flammable solvents are in use.

1.2 When a flame might still appear

If your lab still uses Bunsen burners, they are usually reserved for:

  • Briefly flaming glassware to dry it;
  • Sterilisation in microbiology work (less common in organic labs).

Even in these cases, flames should be used far from solvent bottles and waste containers, and only when your instructor confirms it is safe.

2. Safer options: hot plates and heating mantles

Hot plates and heating mantles remove the naked flame, but they are not risk-free.

2.1 Hot plates

Hot plates are good for:

  • Gentle heating of beakers and flasks;
  • Combining heating and magnetic stirring.

Safer habits:

  • Use appropriate support: place flasks in a beaker or on a ceramic pad when needed, not directly on bare metal if the design does not allow it.
  • Keep the area around the hot plate clear of solvent bottles, paper towels, and plastic items.
  • Turn the control to low or off before plugging in or unplugging.

2.2 Heating mantles

Heating mantles are designed to heat round-bottom flasks more evenly than hot plates.

Safer habits:

  • Use a mantle that fits the flask size properly; avoid “cramming” a larger flask into a smaller mantle.
  • Always support the flask with a clamp and stand, not just resting in the mantle.
  • Do not let liquid overflow into the mantle. If it happens, turn off the power and report it.

Quick question

You finish a reflux experiment and turn off the heating mantle. The round-bottom flask is still very hot and contains flammable solvent. What is the safest thing to do next?

  1. A. Immediately remove the flask from the mantle with bare hands so it cools faster.
  2. B. Leave the flask supported and let it cool in place before handling it.
  3. C. Move the hot flask quickly to another bench to free the mantle.
Show suggested answer

Leave the flask supported and let it cool in place before handling it.
Hot glassware can cause burns and is more likely to break if moved while very hot. Keeping the flask clamped and supported reduces the chance of spills or sudden breakage while the solvent and glass cool down.

3. Preventing fires when heating solvents

Most heating-related fires share a few common features. You can avoid many of them by planning ahead.

3.1 Keep flammable liquids away from hot surfaces

Before you turn on any heater, check:

  • Are solvent bottles stored away from the hot plate or mantle?
  • Is your waste container located somewhere cooler and safer?
  • Is there any spill or residue on the hot surface from a previous user?

If a spill occurs:

  • Turn off the heater if it is safe to do so.
  • Allow the surface to cool if necessary.
  • Wipe the area carefully with appropriate materials, disposing of them as chemical waste if required.

3.2 Control boiling and bumping

Uncontrolled boiling can throw hot liquid out of the flask:

  • Use boiling chips or a stir bar when appropriate.
  • Start with a low heat setting and increase gradually.
  • Never fill a flask more than about half full for boiling or reflux.

4. Glassware and heat: avoiding cracks and burns

4.1 Check glassware before heating

Heating cracked or chipped glassware increases the chance of sudden failure.

Before you heat:

  • Inspect the rim, body, and any joints for cracks or chips.
  • Do not use flawed glassware, especially under reflux, distillation, or vacuum.

4.2 Handling hot glassware

Hot glass often looks exactly like cold glass.

  • Assume glassware on or near heaters is hot.
  • Use heat-resistant gloves or tongs when moving recently heated items.
  • Allow glass to cool on a heat-resistant surface before washing or storing.

5. Checklist: heat safety before, during and after

Before, during and after using heat, you can use this quick checklist:

Before heating

While heating

After heating

6. Safety note

Information on ChemNorth is for educational purposes and small-lab guidance. Always follow your institution’s safety rules and local regulations, and ask your instructor or safety officer if you are unsure about a procedure.

Mini quiz

Which situation is most clearly unsafe in an organic chemistry lab?



Show suggested answer

Placing an open bottle of diethyl ether next to a hot plate that is turned on.
Diethyl ether is a very volatile and highly flammable solvent. Its vapours can travel to the hot surface and ignite, even if the flame or heating element is not in direct contact with the liquid. The other two situations are normally acceptable in a well-managed lab.

Your First Organic Chemistry Lab: A Practical Safety Briefing

Summary
To stay safe in an organic chemistry lab, you should always wear a lab coat, goggles and suitable gloves, keep flames and hot surfaces away from flammable solvents, and handle volatile or toxic chemicals in a fume hood. Never eat, drink or pipet by mouth in the lab, wash your hands when you finish, and avoid using damaged glassware or electrical equipment.

When you walk into an organic chemistry lab for the first time, the benches, glassware and instruments can feel exciting and intimidating at the same time.
This article is meant to be quiet, practical “pre-reading” before you ever light a heater or pour a solvent.

It does not replace your department’s official safety rules. Instead, it helps you understand why those rules exist, and what is most likely to go wrong if you ignore them.

1. Three common types of lab accidents

Most accidents in the organic lab fall into three broad groups:

  1. Fires and explosions – ignition of flammable vapours or reactive chemicals.
  2. Cuts and mechanical injuries – mainly from broken or mishandled glassware.
  3. Exposure to toxic materials – by inhalation, ingestion, or skin absorption.

Once you start noticing which group a situation belongs to, it becomes much easier to see danger coming a few steps earlier.

2. Fires and explosions: controlling ignition sources

Organic chemistry uses a lot of volatile, flammable liquids. Their vapours are heavier than air and can travel along the bench or near the floor to find a flame or spark.

The safest mindset is:

Assume flammable vapour is present whenever you are using low-boiling organic solvents.

The main ignition sources in a teaching lab are:

2.1 Open flames

Open flames include Bunsen burners, alcohol lamps, matches and lighters.

  • Vapours from solvents like diethyl ether, pentane or acetone can ignite even when the flame is a few metres away.
  • For this reason, many organic labs do not allow open flames at all when flammable solvents are in use.

If your lab still uses Bunsen burners, they should only be lit when your instructor explicitly allows it, and never near open bottles of solvent or waste containers.

2.2 Hot surfaces

Hot plates and heating mantles have no visible flame, but their surfaces can easily ignite solvent spilled on them.

Typical problems:

  • A reaction mixture bumps out of a flask onto a hot plate.
  • Someone sets a solvent bottle or beaker directly on a hot heating mantle.
  • The thermostat on a hot plate switches on and off, and the internal spark ignites vapour from an open container nearby.

Practical habits:

  • Keep solvent bottles and waste containers away from heaters.
  • Wipe up spills immediately once equipment has cooled enough to do so.
  • Turn off heaters as soon as you are finished with them.

2.3 Faulty electrical equipment

Frayed power cords, loose plugs, and damaged sockets can produce sparks or overheat.

  • Never use equipment with exposed wires, cracked plugs or scorched insulation.
  • If you notice a problem, unplug the device and report it instead of “making it work this one time”.

2.4 Chemical fires

Some reactions themselves generate enough heat or gas to ignite nearby material:

  • Very reactive metals (such as sodium) reacting with water and releasing hydrogen gas.
  • Strong oxidizing agents mixed with organic material.

You will normally only perform such reactions under close supervision. Read the pre-lab notes carefully and understand where the heat and gas are coming from.

3. Cuts and mechanical injuries: working safely with glass

Glassware is at the heart of the organic lab, and also a major source of minor injuries.

3.1 Breaking glass rods or tubing

When you need to cut glass tubing, the safe method is:

  1. Score a small line around the glass with a file or glass-cutting tool.
  2. Wet the score line with a drop of water to help the crack start cleanly.
  3. Hold the tube with both hands, wrapped in a towel or paper tissue, with thumbs placed opposite the score line.
  4. Gently bend the glass away from the score until it snaps along the line.

Never try to “snap” un-scored glass by brute force – it tends to shatter unpredictably.

3.2 Inserting glass into stoppers

Thermometers and glass tubes are often fitted into rubber or cork stoppers. Done badly, this is a classic way to drive broken glass into the palm of your hand.

Safer technique:

  • Lubricate the end of the glass with a drop of water or glycerol.
  • Hold the stopper in one hand and the glass close to the end that enters the stopper with the other.
  • Rotate the stopper gently while pushing slowly.
  • Never hold the glass far from the stopper and push hard – if it breaks, the broken end can be forced into your hand.

3.3 Chipped or cracked glassware

Before you use any beaker, flask or funnel, quickly check:

  • Are the rims smooth?
  • Is there any crack along the body or near the joint?

If you find chips or cracks:

  • Do not use the item, especially under vacuum or heat.
  • Place it in the designated broken-glass container or follow your lab’s procedure.

A small chip on the lip of a beaker is still sharp enough to slice your finger.

4. Exposure to toxic materials

Even if nothing catches fire and no glass breaks, you can still be harmed by breathing, swallowing or absorbing chemicals.

4.1 Inhalation: use the fume hood

Many organic liquids evaporate readily and have irritating or toxic vapours.

  • A fume hood is designed to remove these vapours from the lab air.
  • Whenever you work with volatile, smelly or toxic substances, assume they belong in the hood unless your instructor explicitly says otherwise.

Practical points:

  • Make sure the hood is on and drawing air before you start.
  • Work at least a hand-span inside the opening, not right at the edge.
  • Keep the sash at the recommended height to maintain good airflow.

4.2 Ingestion: keep chemistry out of your mouth

Ingestion accidents are almost always preventable:

  • Never taste any substance in the lab.
  • Never pipet liquids by mouth – use a pipet bulb or mechanical pipettor.
  • Do not eat or drink in the lab, and do not store food in lab refrigerators.
  • At the end of the session, wash your hands thoroughly with soap and water.

Any food, drink, or lip balm used in the lab can easily become contaminated.

4.3 Skin absorption: protect your skin

Many organic compounds can pass through the skin, especially if they are non-polar and your gloves are not resistant to them.

  • Wear appropriate protective gloves when handling liquids or solids that could irritate or be absorbed through the skin.
  • If a chemical is spilled on your skin:
    • Rinse the area immediately with plenty of water for at least 10–15 minutes.
    • Inform your instructor, even if it doesn’t hurt at once.

Gloves are not all the same. Later, you will learn how to match glove materials (for example, nitrile vs latex) to the solvents you use.

5. A short checklist for your first lab session

Before or during your first organic lab, make sure you can answer these:

1. Do I know where to find…

2. Am I using heat safely?

3. Am I handling glassware correctly?

4. Am I limiting my exposure to chemicals?

6. Final thoughts

The organic chemistry lab will always contain some level of risk, simply because we work with energetic reactions and active molecules.
But with a basic understanding of how accidents actually happen—and with a few good habits—you can keep that risk low enough to learn and explore with confidence.

In future ChemNorth articles, we will look more closely at specific topics: how to choose safe heating equipment, how to handle broken glass, and how to work effectively in the fume hood.

For now, bring this safety briefing with you in your mind the next time you step into the lab. It is the quiet foundation under every successful experiment.